The main pharmaco-therapeutic action: bacteriostatic, in some cases also bactericidal action, semi A / B, inhibits protein synthesis in microbial cells, the drug is susceptible to such M & E: Mycoplasma pneumoniae, Legionella pheumophila, Chlamydia trachomatis i C.pneumoniae, Ureaplasma urealyticum; basically (+) m / basically (streptococci and staphylococci, Listeria monocytogenes, Corynebacterium spp.); gram (-) m / s (Haemophilus influenzae i H. pneumoniae, Corynobacterium spp., Bacillus anthracis; referring to the variable activity against Haemophilus influenzae, a / b should not be used in the treatment of respiratory infections caused by Haemophilus. Indications for use drugs: infection of the upper and lower respiratory tract - pneumonia, bronchitis, otitis media, sinusitis, tonsillitis, pharyngitis, cholecystitis, cholangitis, gonorrhea, urinary tract infections, gastrointestinal tract infections caused by Campylobacter jejuni; diphtheritic carriage, erysipelas, acne, prevention infectious complications (endocarditis) in dental interventions in patients with heart disease, hypersensitivity to penicillin, if Cyomegalovirus for its use. Macrolide and linkozamidy. Method of production of drugs: Table., Coated tablets, 250 mg, 500 mg, tab 100 mg tab-coated powder, oral solution, of 0,1 g, 0,2 g Pharmacotherapeutic group: J01FA10 - Antibacterial agents for systemic use. Indications for use drugs: VDSH infection and upper respiratory tract: tonsillitis, pharyngitis, tonsillitis, sinusitis, otitis media, lower respiratory infections: bacterial bronchitis, Mts bronchitis in the acute stage, interstitial and alveolar pneumonia, infection of the skin and soft tissues (erysipelas, basically repeatedly infected dermatitis), infections, sexually transmitted infections (uncomplicated basically cervicitis), Lyme disease (borrelioz) basically the treatment of the initial stage ( erythema migrans); disease of the Head, Eyes, Ears, Nose, Throat and duodenum associated with Helicobacter pylori. Dosing and Administration of drugs: for adults and children weighing over 40 kg: usually prescribe 300 mg per day in 1 - 2 techniques (ie, 150 mg every 12 hours, or 300 mg every 24 h) treatment duration is 5 - 10 days, depending on the indications and clinical response, disappearance of symptoms after treatment should last at least another 2 days, with strep throat treatment is at least 10 days to prevent relapse or late complications is similar - for the treatment of urethritis, cervicitis and tservikovahinitu; therapy of chlamydial infection can extend to 14 days. The main effect of pharmaco-therapeutic effects of drugs: bacteriostatic action, semi-synthetic and cotton; antibacterial spectrum includes Gram (+) and Gram (-) aerobic Bone Mineral Content anaerobic m / o: aerobic bacteria - staphylococci Polymyalgia Rheumatica metytsylinstiyki strains), streptococci, Corynebacterium spp., Bacillus cereus, Listeria monocytogenes, Neisserria gonorrhoeae, N.meningitidis, Bordetella pertussis, Helicobacter pylori, Gardnerella vaginalis, Branhamella (Moraxella) catarrhalis and Legionella pneumophila; sensitivity of strains of Haemophilus influenzae variable; also here active drug Chlamidia trachomatis, Ureaplasma ureolyticus, Mycoplasma pneumoniae, Rickettsia rickettsii and R.conorii. spr. Side effects and complications in the use of basically nausea, vomiting, diarrhea, basically pain, AR (itching, rash), hepatitis with cholestasis (jaundice, itching, fever, abdominal pain). Indications for use drugs: ear infections, nose and throat (laryngitis, tonsillitis, pharyngitis, sinusitis, otitis media) respiratory infections (bronchitis, pneumonia), urinary tract infections (including infections, sexually transmitted diseases other than gonorrhea); infections of skin and soft tissue (normal acne, boils, anthrax, pyoderma). 250 mg lyophilized powder for preparation of district for basically 500 mg, 1g. vial., powder for suspension for oral, 100 mg / 5 ml, 200 mg / Bronchiolitis Obliterans Organizing Pneumonia ml, 100 ml mh/20, 200 mh/20 mo, 500 ml vial mh/20. coated tablets 50 mg, 100 mg, 150 mg, 300 mg. pneumoniae, Str.pyogenes, Str agalactiae, streptococci groups C, F and G, S.viridans; Staph. species, and Chlamydia trachomatis, Mycoplasma pneumoniae, Ureaplasma basically Treponema pallidum, Borrelia burgdorferi.